| S.No. | NAME OF ADVANCED INTERMEDIATE | RELATED API | CAS NUMBER |
|---|---|---|---|
| 1 | 2-Chloromethyl-3,4-dimethoxypyridine HCl | Pantoprazole | 72830-09-2 |
| 2 | 5-Difluoromethoxy-2-mercapto-1-H-benzimidazole | Pantoprazole | 97963-62-7 |
| 3 | 5-(Difluoro methoxy)-2-{[(3,4 dimethoxypyridin-2-yl)methyl]thio}-1H-benzimidazole (Panto Sulfide) | Pantoprazole | 102625-64-9 |
| 4 | 2-Hydroxymethyl-3,5-dimethyl,4-methoxy pyridine | Omeprazole/Esomeprazole | 86604-78-6 |
| 5 | 2-Chloromethyl-3,5-dimethyl-4-methoxypyridine HCl | Omeprazole/Esomeprazole | 86604-75-3 |
| 6 | 5-Methoxy-2[[(4-methoxy-3,5-dimethyl-2-methylpyridyl]1H-thio benzimidazole (Ome sulfide) | Omeprazole/Esomeprazole | 73590-85-9 |
| 7 | N-Methyl-1-naphthalene methylamine HCl | Terbinafine HCl | 65473-13-4 |
| 8 | N-Methyl-1-naphthalene methylamine (Base) | Terbinafine HCl | 14489-75-9 |
| 9 | 4-(4-Chlorophenyl)-4-hydroxy piperidine | Haloperidol/Loperamide HCl | 39512-49-7 |
| 10 | Dihydro-N,N-dimethyl-3,3-diphenyl-2(3H)-furaniminium bromide | Loperamide | 37743-18-3 |
| 11 | 2-Cyano-3-[2(3-chloro phenyl) ethyl]pyridine (L-5) | Loratadine | 31255-57-9 |
| 12 | 8-Chloro-6,11-dihydro-11-(1-methyl-4-piperidinylidene)-5H-benzo[5,6] cyclohepta[1,2-b]pyridine (N-Merthyl Desloratadine) | Loratadine | 38092-89-6 |
| 13 | 2-N-Butyl-1,3-diazaspiro(4,4)non-1-en-4-one Hydrochloride (Spiro Compound) | Irbesartan | 151257-01-1 |
| 14 | N-(Triphenylmethyl)-5-(4’bromomethyl-biphenyl-2-yl)tetrzole | Losartan potassium, Irbesartan, Valsartan, Olmesartan medoxomil, Fimasartan Potassium Trihydrate | 124750-51-2 |
| 15 | 2-Butyl-4-chloro-5-formylimidazole | Losartan potassium, Eprosartan mesylate | 83857-96-9 |
| 16 | 2-Butyl-4-chloro-1-[[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-1H-imidazole-5-methanol | Losartan potassium, Allisartan Isoproxil | 114798-26-4 |
| 17 | 6-Fluoro-3-hydroxypyrazine-2-carbonitrile dicyclohexylamine | Favipiravir | 1137606-74-6 |
| 18 | 1-(3-Chloropropyl)-1,3-dihydro-2H-benzimidazol-2-one | Domperidone | 62780-89-6 |
| 19 | 5-Chloro-1-piperidine-4-yl-1,3-dihydro-2H-benzimidazol-2-one | Domperidone | 53786-28-0 |
| 20 | Dibenzosuberone | Amitriptyline HCl/Nortriptyline HCl | 1210-35-1 |
| 21 | Dibenzosuberenone | Cyclobenzaprine HCl/Cyproheptadine HCl, | 2222-33-5 |
| 22 | (S)-1-(2-Chloroacetyl)pyrrolidine-2-carbonitrile | Vildagliptin | 207557-35-5 |
| 23 | (S)-1-(Chloroacetyl)-2-pyrrolidine carboxamide | Vildagliptin | 214398-99-9 |
| 24 | 3-Aminoadamantan-1-ol | Vildagliptin | 702-82-9 |
| 25 | N-(5-Amino-2-methylphenyl)-4-(3-pyridyl)-2-pyrimidineamine | Imatinib | 152460-10-1 |
| 26 | 4-[(4-Methylpiperazin-1-yl)methyl]benzoic acid dihydrochloride | Imatinib | 106261-49-8 |
| 27 | 4-[(4-Methylpiperazin-1-yl)methyl]-N-[4-methyl-3-[(4-pyridin-3-ylpyrimidin-2-yl)amino]phenyl]benzamide (Imatinib base) | Imatinib | 152459-95-5 |
| 28 | 3-(Trifluoromethyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazine hydrochloride | Sitagliptin | 762240-92-6 |
| 29 | Methyl 2-(4-(4-chlorobutanoyl)phenyl)-2-methylpropanoate | Fexofenadine | 154477-54-0 |
| 30 | alpha,alpha-Diphenyl-4-piperidinomethanol | Fexofenadine | 115-46-8 |
| 31 | Methyl 4-[4-[4-hydroxydiphenylmethyl)-1-piperidinyl] 1-oxobutyl]-2,2-dimethyl benzene acetate | Fexofenadine | 154477-55-1 |
| 32 | 1-(2,3-Dichlorophenyl)Piperazine Hydrochloride (DCPH) | 119532-26-2 | Aripiprazole |
| 33 | 2-(4-(Cyclopropanecarboyl)Phenyl)-2-Methylpropanoic Acid | 162096-54-0 | Fexofenadine |
| 34 | 4,7-dichloroquinoline (4,7-DCQ) | 86-98-6 | Hydroxychloroquine sulfate |
| 35 | 5-(N-Ethyl-N-2-hydroxyethyl amino)-2 -pentylamine (HNDA) | 69559-11-1 | Hydroxychloroquine sulfate |
| 36 | 3-Acetyl pyridine | 350-03-8 | Imatinib |
| 37 | 7,8-Dimethoxy-1,3,4,5-tetrahydrobenzo[d]azepin-2-one | 20925-64-8 | Ivabradine |
| 38 | 7,8-Dimethoxy-1,3-dihydro-2H-3-benzazepin-2-one | 73942-87-7 | Ivabradine |
| 39 | 2-(Bromomethyl)-3-nitrobenzoic Acid Methyl Ester | 98475-07-1 | Lenalidomide |
| 40 | 3-Aminopiperidine-2,6-dione hydrochloride (3AP) | 24666-56-6 | Lenalidomide |
| 41 | 5-Methylnicotinic acid | 3222-49-9 | Rupatadine |
| 42 | 3-(Chloromethyl)-5-methylpyridine hydrochloride | 1007089-84-0 | Rupatadine |
| 43 | 4-Chloropyrrolo[2,3-d]pyrimidine | 3680-69-1 | Tofacitinib |
| 44 | 2,2,14,14-Tetramethyl-8-oxopentadecanedioic acid diethyl ester | 738606-43-4 | Bempedoic Acid |
| 45 | 2,2,14,14-Tetramethyl-8-oxopentadecanedioic acid | 413624-71-2 | Bempedoic Acid |
| 46 | Isocyano methyl Sulfonyl Methyl benzene | 36635-61-7 | Bempedoic Acid |
| 47 | 4,5-Dimethoxy-1-cyanobenzocyclobutane | 35202-54-1 | Ivabradine HCl |
| 48 | (1S)-4,5-Dimethoxy-1-[(methylamino)methyl]benzocyclobutane hydrochloride | 866783-13-3 | Ivabradine HCl |
| S.No. | NAME OF ADVANCED INTERMEDIATE | RELATED API | CAS NUMBER |
|---|---|---|---|
| 1 | 2-Chloromethyl-3,4-dimethoxypyridine HCl | Pantoprazole | 72830-09-2 |
| 2 | 5-Difluoromethoxy-2-mercapto-1-H-benzimidazole | Pantoprazole | 97963-62-7 |
| 3 | 5-(Difluoro methoxy)-2-{[(3,4 dimethoxypyridin-2-yl)methyl]thio}-1H-benzimidazole (Panto Sulfide) | Pantoprazole | 102625-64-9 |
| 4 | 2-Hydroxymethyl-3,5-dimethyl,4-methoxy pyridine | Omeprazole/Esomeprazole | 86604-78-6 |
| 5 | 2-Chloromethyl-3,5-dimethyl-4-methoxypyridine HCl | Omeprazole/Esomeprazole | 86604-75-3 |
| 6 | 5-Methoxy-2[[(4-methoxy-3,5-dimethyl-2-methylpyridyl]1H-thio benzimidazole (Ome sulfide) | Omeprazole/Esomeprazole | 73590-85-9 |
| 7 | N-Methyl-1-naphthalene methylamine HCl | Terbinafine HCl | 65473-13-4 |
| 8 | N-Methyl-1-naphthalene methylamine (Base) | Terbinafine HCl | 14489-75-9 |
| 9 | 4-(4-Chlorophenyl)-4-hydroxy piperidine | Haloperidol/Loperamide HCl | 39512-49-7 |
| 10 | Dihydro-N,N-dimethyl-3,3-diphenyl-2(3H)-furaniminium bromide | Loperamide | 37743-18-3 |
| 11 | 8-Chloro-10,11-dihydro-4-aza-5H-dibenzo(a,d)-Cyclohepten-5-One / (Loraketone) | Loratadine | 31251-41-9 |
| 12 | 2-Cyano-3-[2(3-chloro phenyl) ethyl]pyridine (L-5) | Loratadine | 31255-57-9 |
| 13 | 8-Chloro-6,11-dihydro-11-(1-methyl-4-piperidinylidene)-5H-benzo[5,6] cyclohepta[1,2-b]pyridine (N-Merthyl Desloratadine) | Loratadine | 38092-89-6 |
| 14 | 2-N-Butyl-1,3-diazaspiro(4,4)non-1-en-4-one Hydrochloride (Spiro Compound) | Irbesartan | 151257-01-1 |
| 15 | N-(Triphenylmethyl)-5-(4’bromomethyl-biphenyl-2-yl)tetrzole | Losartan potassium, Irbesartan, Valsartan, Olmesartan medoxomil, Fimasartan Potassium Trihydrate | 124750-51-2 |
| 16 | 2-Butyl-4-chloro-5-formylimidazole | Losartan potassium, Eprosartan mesylate | 83857-96-9 |
| 17 | 2-Butyl-4-chloro-1-[[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-1H-imidazole-5-methanol | Losartan potassium, Allisartan Isoproxil | 114798-26-4 |
| 18 | 2-Cyano-4’-bromomethylbiphenyl | Losartan potassium, Irbesartan, Valsartan, Olmesartan medoxomil, Fimasartan Potassium Trihydrate | 114772-54-2 |
| 19 | 6-Fluoro-3-hydroxypyrazine-2-carbonitrile dicyclohexylamine | Favipiravir | 1137606-74-6 |
| 20 | 1-(3-Chloropropyl)-1,3-dihydro-2H-benzimidazol-2-one | Domperidone | 62780-89-6 |
| 21 | 5-Chloro-1-piperidine-4-yl-1,3-dihydro-2H-benzimidazol-2-one | Domperidone | 53786-28-0 |
| 22 | Dibenzosuberone | Amitriptyline HCl/Nortriptyline HCl | 1210-35-1 |
| 23 | Dibenzosuberenone | Cyclobenzaprine HCl/Cyproheptadine HCl, | 2222-33-5 |
| 24 | (S)-1-(2-Chloroacetyl)pyrrolidine-2-carbonitrile | Vildagliptin | 207557-35-5 |
| 25 | (S)-1-(Chloroacetyl)-2-pyrrolidine carboxamide | Vildagliptin | 214398-99-9 |
| 26 | 3-Aminoadamantan-1-ol | Vildagliptin | 702-82-9 |
| 27 | N-(5-Amino-2-methylphenyl)-4-(3-pyridyl)-2-pyrimidineamine | Imatinib | 152460-10-1 |
| 28 | 4-[(4-Methylpiperazin-1-yl)methyl]benzoic acid dihydrochloride | Imatinib | 106261-49-8 |
| 29 | 4-[(4-Methylpiperazin-1-yl)methyl]-N-[4-methyl-3-[(4-pyridin-3-ylpyrimidin-2-yl)amino]phenyl]benzamide (Imatinib base) | Imatinib | 152459-95-5 |
| 30 | 3-(Trifluoromethyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazine hydrochloride | Sitagliptin | 762240-92-6 |
| 31 | Boc-(R)-3-Amino-4-(2,4,5-trifluorophenyl)butanoic acid | Sitagliptin | 486460-00-8 |
| 32 | 1-(3-(Trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)-4-(2,4,5-trifluorophenyl)butane-1,3-dione | Sitagliptin | 764667-65-4 |
| 33 | Methyl 2-(4-(4-chlorobutanoyl)phenyl)-2-methylpropanoate | Fexofenadine | 154477-54-0 |
| 34 | alpha,alpha-Diphenyl-4-piperidinomethanol | Fexofenadine | 115-46-8 |
| 35 | Methyl 4-[4-[4-hydroxydiphenylmethyl)-1-piperidinyl] 1-oxobutyl]-2,2-dimethyl benzene acetate | Fexofenadine | 154477-55-1 |
| 36 | 6,8-Dichloro ethyl caprylate | Alpha Lipoic acid | 41443-60-1 |
| 37 | 2-N-Propyl-4-methyl-6-(1-methyl benzimidazole-2-yl)benzimidazole | Telmisartan | 152628-02-09 |
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