INTERMEDIATES – TAGOOR LABORATORIES Pvt. Ltd

advanced intermediates

S.No.	NAME OF ADVANCED INTERMEDIATE	RELATED API	CAS NUMBER
1	2-Chloromethyl-3,4-dimethoxypyridine HCl	Pantoprazole	72830-09-2
2	5-Difluoromethoxy-2-mercapto-1-H-benzimidazole	Pantoprazole	97963-62-7
3	5-(Difluoro methoxy)-2-{[(3,4 dimethoxypyridin-2-yl)methyl]thio}-1H-benzimidazole (Panto Sulfide)	Pantoprazole	102625-64-9
4	2-Hydroxymethyl-3,5-dimethyl,4-methoxy pyridine	Omeprazole/Esomeprazole	86604-78-6
5	2-Chloromethyl-3,5-dimethyl-4-methoxypyridine HCl	Omeprazole/Esomeprazole	86604-75-3
6	5-Methoxy-2[[(4-methoxy-3,5-dimethyl-2-methylpyridyl]1H-thio benzimidazole (Ome sulfide)	Omeprazole/Esomeprazole	73590-85-9
7	1-(3-Chloropropyl)-1,3-dihydro-2H-benzimidazol-2-one (DOM-II)	Domperidone	62780-89-6
8	5-Chloro-1-piperidine-4-yl-1,3-dihydro-2H-benzimidazol-2-one (DOM-IX)	Domperidone	53786-28-0
9	2-Chloromethyl-3-methyl-4-(2,2,2-trifluoroethoxy)pyridine hydrochloride (Lanso Chloro)	Lansoprazole/Dexlansoprazole	127337-60-4
10	2-[3-Methyl-4-(2,2,2-trifluoroethoxy)-2-pyridylmethylthio]benzimidazole (Lanso Sulfide)	Lansoprazole/Dexlansoprazole	103577-40-8
11	2-Cyano-3-[2(3-chloro phenyl) ethyl]pyridine (L-5)	Loratadine/Desloratadine	31255-57-9
12	8-Chloro-6,11-dihydro-11-(1-methyl-4-piperidinylidene)-5H-benzo[5,6] cyclohepta[1,2-b]pyridine (N-Merthyl Desloratadine)	Loratadine/Desloratadine	38092-89-6
13	N-Methyl-4-chloropiperidine	Loratadine/Desloratadine	5570-77-4
14	5-Methylnicotinic acid	Rupatadine	3222-49-9
15	3-(Chloromethyl)-5-methylpyridine hydrochloride	Rupatadine	1007089-84-0
16	2-(2-(4-(2-(4-(1-(2-ethoxyethyl)-1H-benzo[d]imidazol-2yl)piperidin-1-yl)ethyl)phenyl)propan-2-yl)-4,4-dimethyl-4,5-dihydrooxazole	Bilastine	202189-77-3
17	2-(1-(4-(2-(4,4-dimethyl-4,5-dihydrooxazol-2-yl)propan- 2-yl)phenethyl)piperidin-4-yl)-1H-benzo[d]imidazole	Bilastine	202189-81-9
18	2-[4-[1-(4,4-dimethyl-5H-oxazol-2-yl)-1-methylethyl] phenyl]ethyl 4-methylbenzenesulfonate	Bilastine	202189-76-2
19	2-(4-(2-chloroethyl)phenyl)-2-methylpropanoic acid	Bilastine	2199440-16-7
20	2-(4-(2-chloroacetyl)phenyl)-2-methylpropanoic acid	Bilastine	2199440-15-6
21	methyl 2-(4-(2-chloroethyl)phenyl)-2-methylpropanoate	Bilastine	1181267-33-3
22	1H-Benzimidazole, 1-(2-ethoxyethyl)-2-(4-piperidinyl)- hydrochloride	Bilastine	1841081-72-8
23	methyl 2-(4-(2-(4-(1-(2-ethoxyethyl)-1H-benzo[d]imidazol-2-yl)piperidin-1-yl)ethyl)phenyl)-2-methylpropanoate	Bilastine	1181267-38-8
24	2-Ethoxyethyl-4-methylbenzenesulfonate	Bilastine	17178-11-9
25	2-Piperidin-4-yl-1H-benzoimidazole	Bilastine	38385-95-4
26	Isonipecotic acid/4-Piperidinecarboxylic acid	Bilastine	498-94-2
27	Methyl isonipecotate	Bilastine	2971-79-1
28	Ethyl isonipecotate	Bilastine	1126-09-6
29	Alpha,alpha-Diphenyl-4-piperidinomethanol (Azacyclonol)	Fexofenadine	115-46-8
30	Methyl 2-(4-(4-chlorobutanoyl)phenyl)-2-methylpropanoate	Fexofenadine	154477-54-0
31	Methyl 4-[4-[4-hydroxydiphenylmethyl)-1-piperidinyl] 1-oxobutyl]-2,2-dimethyl phenyl acetate	Fexofenadine	154477-55-1
32	2-(4-(Cyclopropanecarboyl)Phenyl)-2-Methylpropanoic Acid	Fexofenadine	162096-54-0
33	Dibenzosuberenone	Cyclobenzaprine HCl/Cyproheptadine HCl	2222-33-5
34	3-Aminoadamantan-1-ol	Vildagliptin	702-82-9
35	(S)-1-(2-Chloroacetyl) pyrrolidine-2-carbonitrile	Vildagliptin	207557-35-5
36	3-(3-Chloropropyl)-1,3-dihydro-7,8-dimethoxy-2H-3-benzazepin-2-one	Ivabradine HCl	85175-59-3
37	7,8-Dimethoxy-1,3,4,5-tetrahydrobenzo[d]azepin-2-one	Ivabradine HCl	20925-64-8
38	7,8-Dimethoxy-1,3-dihydro-2H-3-benzazepin-2-one	Ivabradine HCl	73942-87-7
39	4,5-Dimethoxy-1-cyanobenzocyclobutane	Ivabradine HCl	35202-54-1
40	(1S)-4,5-Dimethoxy-1-[(methylamino)methyl]benzocyclobutane hydrochloride	Ivabradine HCl	866783-13-3
41	tert-Butyl ((1R,2S,5S)-2-amino-5-(dimethylcarbamoyl)cyclohexyl)carbamate	Edoxaban	365998-36-3
42	5-Methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine-2-carboxylic acid hydrochloride	Edoxaban	720720-96-7
43	2-[(5-Chloropyridin-2-yl)amino]-2-oxoacetic acid ethyl ester monohydrochloride	Edoxaban	1243308-37-3
44	4,6-dichloro-2-propylthiopyrimidine-5-amine	Ticagrelor	145783-15-9
45	4-[(4-Methylpiperazin-1-yl)methyl]benzoic acid dihydrochloride	Imatinib	106261-49-8
46	4-[(4-Methylpiperazin-1-yl)methyl]-N-[4-methyl-3-[(4-pyridin-3-ylpyrimidin-2-yl)amino]phenyl]benzamide (Imatinib base)	Imatinib	152459-95-5
47	N-(5-Amino-2-methylphenyl)-4-(3-pyridyl)-2-pyrimidineamine	Imatinib	152460-10-1
48	3-Acetyl pyridine	Imatinib	350-03-8
49	2-(Bromomethyl)-3-nitrobenzoic Acid Methyl Ester	Lenalidomide	98475-07-1
50	3-Aminopiperidine-2,6-dione hydrochloride (3AP)	Lenalidomide	24666-56-6
51	4-Chloro-6,7-dimethoxyquinoline	Cabozantinib	35654-56-9
52	1-((4-Fluoro phenyl) Carbamoyl) Cyclopropane Carboxylic acid	Cabozantinib	849217-48-7
53	4-((6,7-Dimethoxyquinolin-4-yl)oxy)aniline	Cabozantinib	190728-25-7
54	Cyclopropane-1,1-dicarboxylic acid methyl ester	Cabozantinib	113020-21-6
55	Diethyl cyclopropane-1,1-dicarboxylate	Cabozantinib	1559-02-0
56	1,1-Cyclopropanedicarboxylic acid	Cabozantinib	598-10-7
57	1-Methyl-4-(piperidin-4-yl) piperazine	Golvatinib, Brigatinib	53617-36-0
58	4-(Dimethoxymethyl)piperidine	Vepdegestrant	188646-83-5
59	4,7-dichloroquinoline (4,7-DCQ)	Hydroxychloroquine sulfate	86-98-6
60	5-(N-Ethyl-N-2-hydroxyethyl amino)-2 -pentylamine (HNDA)	Hydroxychloroquine sulfate	69559-11-1
61	(3R,4R)-N,4-Dimethyl-1-(phenylmethyl)-3-piperidinamine dihydrochloride	Tofacitinib	1062580-52-2
62	N-Methyl-1-naphthalene methylamine (Base)	Terbinafine HCl	14489-75-9
63	N-Methyl-1-naphthalene methylamine HCl	Terbinafine HCl	65473-13-4
64	4-(4-Chlorophenyl)-4-hydroxy piperidine (PCP)	Loperamide / Haloperidol	39512-49-7
65	Dihydro-N,N-dimethyl-3,3-diphenyl-2(3H)-furaniminium bromide	Loperamide HCl	37743-18-3
66	1-(2,3-Dichlorophenyl)Piperazine Hydrochloride (DCPH)	Aripiprazole	119532-26-2
67	2-N-Butyl-1,3-diazaspiro(4,4)non-1-en-4-one Hydrochloride (Spiro Compound)	Irbesartan	151257-01-1
68	Phthaloyl Amlodipine	Amlodipine	88150-62-3
69	Dibenzosuberone	Amitriptyline HCl/Nortriptyline HCl	1210-35-1
70	2-Amino-5-chloro-N,3-dimethylbenzamide	Chlorantraniliprole	890707-28-5

S.No.	NAME OF ADVANCED INTERMEDIATE	RELATED API	CAS NUMBER
1	2-Chloromethyl-3,4-dimethoxypyridine HCl	Pantoprazole	72830-09-2
2	5-Difluoromethoxy-2-mercapto-1-H-benzimidazole	Pantoprazole	97963-62-7
3	5-(Difluoro methoxy)-2-{[(3,4 dimethoxypyridin-2-yl)methyl]thio}-1H-benzimidazole (Panto Sulfide)	Pantoprazole	102625-64-9
4	2-Hydroxymethyl-3,5-dimethyl,4-methoxy pyridine	Omeprazole/Esomeprazole	86604-78-6
5	2-Chloromethyl-3,5-dimethyl-4-methoxypyridine HCl	Omeprazole/Esomeprazole	86604-75-3
6	5-Methoxy-2[[(4-methoxy-3,5-dimethyl-2-methylpyridyl]1H-thio benzimidazole (Ome sulfide)	Omeprazole/Esomeprazole	73590-85-9
7	N-Methyl-1-naphthalene methylamine HCl	Terbinafine HCl	65473-13-4
8	N-Methyl-1-naphthalene methylamine (Base)	Terbinafine HCl	14489-75-9
9	4-(4-Chlorophenyl)-4-hydroxy piperidine	Haloperidol/Loperamide HCl	39512-49-7
10	Dihydro-N,N-dimethyl-3,3-diphenyl-2(3H)-furaniminium bromide	Loperamide	37743-18-3
11	8-Chloro-10,11-dihydro-4-aza-5H-dibenzo(a,d)-Cyclohepten-5-One / (Loraketone)	Loratadine	31251-41-9
12	2-Cyano-3-[2(3-chloro phenyl) ethyl]pyridine (L-5)	Loratadine	31255-57-9
13	8-Chloro-6,11-dihydro-11-(1-methyl-4-piperidinylidene)-5H-benzo[5,6] cyclohepta[1,2-b]pyridine (N-Merthyl Desloratadine)	Loratadine	38092-89-6
14	2-N-Butyl-1,3-diazaspiro(4,4)non-1-en-4-one Hydrochloride (Spiro Compound)	Irbesartan	151257-01-1
15	N-(Triphenylmethyl)-5-(4’bromomethyl-biphenyl-2-yl)tetrzole	Losartan potassium, Irbesartan, Valsartan, Olmesartan medoxomil, Fimasartan Potassium Trihydrate	124750-51-2
16	2-Butyl-4-chloro-5-formylimidazole	Losartan potassium, Eprosartan mesylate	83857-96-9
17	2-Butyl-4-chloro-1-[[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-1H-imidazole-5-methanol	Losartan potassium, Allisartan Isoproxil	114798-26-4
18	2-Cyano-4’-bromomethylbiphenyl	Losartan potassium, Irbesartan, Valsartan, Olmesartan medoxomil, Fimasartan Potassium Trihydrate	114772-54-2
19	6-Fluoro-3-hydroxypyrazine-2-carbonitrile dicyclohexylamine	Favipiravir	1137606-74-6
20	1-(3-Chloropropyl)-1,3-dihydro-2H-benzimidazol-2-one	Domperidone	62780-89-6
21	5-Chloro-1-piperidine-4-yl-1,3-dihydro-2H-benzimidazol-2-one	Domperidone	53786-28-0
22	Dibenzosuberone	Amitriptyline HCl/Nortriptyline HCl	1210-35-1
23	Dibenzosuberenone	Cyclobenzaprine HCl/Cyproheptadine HCl,	2222-33-5
24	(S)-1-(2-Chloroacetyl)pyrrolidine-2-carbonitrile	Vildagliptin	207557-35-5
25	(S)-1-(Chloroacetyl)-2-pyrrolidine carboxamide	Vildagliptin	214398-99-9
26	3-Aminoadamantan-1-ol	Vildagliptin	702-82-9
27	N-(5-Amino-2-methylphenyl)-4-(3-pyridyl)-2-pyrimidineamine	Imatinib	152460-10-1
28	4-[(4-Methylpiperazin-1-yl)methyl]benzoic acid dihydrochloride	Imatinib	106261-49-8
29	4-[(4-Methylpiperazin-1-yl)methyl]-N-[4-methyl-3-[(4-pyridin-3-ylpyrimidin-2-yl)amino]phenyl]benzamide (Imatinib base)	Imatinib	152459-95-5
30	3-(Trifluoromethyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazine hydrochloride	Sitagliptin	762240-92-6
31	Boc-(R)-3-Amino-4-(2,4,5-trifluorophenyl)butanoic acid	Sitagliptin	486460-00-8
32	1-(3-(Trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)-4-(2,4,5-trifluorophenyl)butane-1,3-dione	Sitagliptin	764667-65-4
33	Methyl 2-(4-(4-chlorobutanoyl)phenyl)-2-methylpropanoate	Fexofenadine	154477-54-0
34	alpha,alpha-Diphenyl-4-piperidinomethanol	Fexofenadine	115-46-8
35	Methyl 4-[4-[4-hydroxydiphenylmethyl)-1-piperidinyl] 1-oxobutyl]-2,2-dimethyl benzene acetate	Fexofenadine	154477-55-1
36	6,8-Dichloro ethyl caprylate	Alpha Lipoic acid	41443-60-1
37	2-N-Propyl-4-methyl-6-(1-methyl benzimidazole-2-yl)benzimidazole	Telmisartan	152628-02-09

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